Two item ions at m/z 324 and 253 in the spectra of metabolites M3.1 and M3.two had been shaped by cleavage of the indazole facet chains, indicating the guardian framework wasn't modified except for the terminal methyl ester. As An important metabolites, ester hydrolysis metabolites M3 group can be employed https://fubinacadrug94824.timeblog.net/67273302/metabolite-3-for-dummies